EP3498705B1 - 2-Acetyl-6-(2-(2-(4-Bromobenzylidene)hydrazinyl)thiazole-4-Yl)-3,7,9-Trihydroxy-8,9b-Dimethyldibenzo[b,d]furan-1(9bh)-One Exhibiting an Inhibitory Effect on Human Tyrosyl-DNA-Phosphodiesterase 1 Enzyme