US8859567B2 - Hydrate of 1-{(2s)-2-Amino-4-[2,4-Bis(trifluoromethyl)-5,8-Di-Hydropyrido[3,4-D]pyrimidin-7(6h)-Yl]-4-Oxobutyl}-5,5-Difluoro-Piperidin-2-One Tartrate