EP4356973A3 - 6-(4-AMINO-3-METHYL-2-OXA-8-AZASPIRO[4.5]DECAN-8-YL)-3-(2,3-DICHLOROPHENYL)-2-METHYLPYRIMIDIN-4(3H)-ONE DERIVATIVES AND RELATED COMPOUNDS AS PTPN11 (SHP2) INHIBITORS FOR TREATING CANCER